The trip from Sao Paulo to Santa Cruz by bus takes around 36 hours, covering 2,084 km. The duration may vary
depending on the time of year, since high tourism months may cause large
traffic at the border, which is in the town of Puerto Quijarro.
Buses leave every day from the Terminal Barra Funda, on Avenida
Auro Soares de Moura Andrade, at 3:00pm and they arrive at the bimodal terminal
of Santa Cruz, located on Avenida Montes. You can also travel between these two
cities by a combination of bus and train. In this case you would have to take a
bus from Sao Paulo to the border town of Puerto Quijarro. From there you can
take a train to Santa Cruz.
Tickets Bolivia lets you book your tickets online for your
bus trip from Santa Cruz to Sao Paulo, with reliable bus and train companies
and the comfort of paying online by credit card, debit card or via PayPal.